AKR1C1 Antibody (PACO55386)
- SKU:
- PACO55386
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | AKR1C1 Antibody (PACO55386) |
抗体コード: | PACO55386 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Aldo-keto reductase family 1 member C1 protein (219-323AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of HepG2 cells with PACO55386 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid, concentration. Has a low bile-binding ability. May play a role in myelin formation. |
シノニム: | Aldo-keto reductase family 1 member C1 (EC 1.1.1) (20-alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (EC 1.1.1.149) (Chlordecone reductase homolog HAKRC) (Dihydrodiol dehydrogenase 1/2) (DD1/DD2) (High-affinity hepatic bile acid, binding protein) (HBAB) (Indanol dehydrogenase) (EC 1.1.1.112) (Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase) (EC 1.3.1.20), AKR1C1, DDH DDH1 |
UniProt Protein Function: | Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation. |
NCBI Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q04828 |
NCBI GenInfo Identifier: | 416877 |
NCBI Gene ID: | 1645 |
NCBI Accession: | Q04828.1 |
UniProt Secondary Accession: | Q04828,P52896, Q5SR15, Q7M4N2, Q9UCX2, |
UniProt Related Accession: | Q04828 |
Molecular Weight: | 36 kDa |
NCBI Full Name: | Aldo-keto reductase family 1 member C1 |
NCBI Synonym Full Names: | aldo-keto reductase family 1 member C1 |
NCBI Official Symbol: | AKR1C1 |
NCBI Official Synonym Symbols: | C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD |
NCBI Protein Information: | aldo-keto reductase family 1 member C1 |
UniProt Protein Name: | Aldo-keto reductase family 1 member C1 |
UniProt Synonym Protein Names: | 20-alpha-hydroxysteroid dehydrogenase (EC:1.1.1.149 |
Protein Family: | Aldo-keto reductase family |
UniProt Gene Name: | AKR1C1 |
Antibodies | ELISA Kits |
Anti-AKR1C1 Antibody (CAB13004) | Human AKR1C1 ELISA Kit |
AKR1C1 Antibody (PACO03563) | Human Aldo-keto reductase family 1 member C1 (AKR1C1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |