AK1 Antibody, Biotin conjugated (PACO24838)
- SKU:
- PACO24838
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | AK1 Antibody, Biotin conjugated (PACO24838) |
抗体コード: | PACO24838 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Adenylate kinase isoenzyme 1 protein (1-194AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. |
シノニム: | Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase), AK1 |
UniProt Protein Function: | AK1: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Small ubiquitous enzyme involved in energy metabolism and nucleotide synthesis that is essential for maintenance and cell growth. Defects in AK1 are the cause of hemolytic anemia due to adenylate kinase deficiency (HAAKD). Belongs to the adenylate kinase family. |
UniProt Protein Details: | Protein type:EC 2.7.4.6; Kinase, other; Nucleotide Metabolism - purine; EC 2.7.4.3 Chromosomal Location of Human Ortholog: 9q34.1 Cellular Component: cytoplasm; cytosol Molecular Function:adenylate kinase activity; nucleoside diphosphate kinase activity Biological Process: nucleobase, nucleoside and nucleotide interconversion; nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process Disease: Adenylate Kinase Deficiency, Hemolytic Anemia Due To |
NCBI Summary: | This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
UniProt Code: | P00568 |
NCBI GenInfo Identifier: | 20178288 |
NCBI Gene ID: | 203 |
NCBI Accession: | P00568.3 |
UniProt Secondary Accession: | P00568,Q9BVK9, Q9UQC7, |
UniProt Related Accession: | P00568 |
Molecular Weight: | 21,635 Da |
NCBI Full Name: | Adenylate kinase isoenzyme 1 |
NCBI Synonym Full Names: | adenylate kinase 1 |
NCBI Official Symbol: | AK1 |
NCBI Official Synonym Symbols: | HTL-S-58j |
NCBI Protein Information: | adenylate kinase isoenzyme 1 |
UniProt Protein Name: | Adenylate kinase isoenzyme 1 |
UniProt Synonym Protein Names: | ATP-AMP transphosphorylase 1 |
Protein Family: | Adenylate kinase |
UniProt Gene Name: | AK1 |
UniProt Entry Name: | KAD1_HUMAN |