Aif1 Antibody, HRP conjugated (PACO24825)
- SKU:
- PACO24825
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | Aif1 Antibody, HRP conjugated (PACO24825) |
抗体コード: | PACO24825 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Allograft inflammatory factor 1 protein (2-147AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
シノニム: | Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1), Aif1, Iba1 |
UniProt Protein Function: | AIF1: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. 3 isoforms of the human protein are produced by alternative splicing.Protein type: CytoskeletalCellular Component: actin filament; cell projection; cytoplasm; cytoskeleton; cytosol; lamellipodium; membrane; nucleus; perikaryon; perinuclear region of cytoplasm; phagocytic cup; plasma membrane; ruffleMolecular Function: actin binding; actin filament binding; calcium ion binding; metal ion binding; protein bindingBiological Process: actin filament bundle formation; actin filament polymerization; microglial cell activation; negative regulation of apoptosis; negative regulation of smooth muscle cell proliferation; phagocytosis, engulfment; positive regulation of cell migration; positive regulation of muscle hyperplasia; positive regulation of nitric oxide biosynthetic process; positive regulation of protein amino acid phosphorylation; positive regulation of smooth muscle cell proliferation; positive regulation of T cell proliferation; Rac protein signal transduction |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O70200 |
NCBI GenInfo Identifier: | 9506379 |
NCBI Gene ID: | 11629 |
NCBI Accession: | NP_062340.1 |
UniProt Secondary Accession: | O70200 |
UniProt Related Accession: | O70200 |
Molecular Weight: | 16,911 Da |
NCBI Full Name: | allograft inflammatory factor 1 |
NCBI Synonym Full Names: | allograft inflammatory factor 1 |
NCBI Official Symbol: | Aif1 |
NCBI Official Synonym Symbols: | G1; Iba1; AIF-1; AI607846; D17H6S50E |
NCBI Protein Information: | allograft inflammatory factor 1 |
UniProt Protein Name: | Allograft inflammatory factor 1 |
UniProt Synonym Protein Names: | Ionized calcium-binding adapter molecule 1 |
Protein Family: | Apoptosis-inducing factor |
UniProt Gene Name: | Aif1 |
UniProt Entry Name: | AIF1_MOUSE |