Agxt Antibody (PACO24811)
- SKU:
- PACO24811
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | Agxt Antibody (PACO24811) |
抗体コード: | PACO24811 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Serine--pyruvate aminotransferase, mitochondrial protein (25-414AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). |
シノニム: | Serine--pyruvate aminotransferase, mitochondrial (SPT) (EC 2.6.1.51) (Alanine--glyoxylate aminotransferase) (AGT) (EC 2.6.1.44), Agxt, Agxt1 |
UniProt Protein Function: | AGXT: Defects in AGXT are the cause of hyperoxaluria primary type 1 (HP1); also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.6.1.44; Motility/polarity/chemotaxis; Transferase; EC 2.6.1.51; Mitochondrial; Amino Acid Metabolism - glycine, serine and threonineCellular Component: mitochondrial matrix; mitochondrion; peroxisomal matrix; peroxisomeMolecular Function: alanine-glyoxylate transaminase activity; amino acid binding; catalytic activity; protein homodimerization activity; protein self-association; pyridoxal phosphate binding; receptor binding; serine-pyruvate transaminase activity; transaminase activity; transferase activityBiological Process: glycine biosynthetic process, by transamination of glyoxylate; glyoxylate catabolic process; glyoxylate metabolic process; L-alanine catabolic process; L-cysteine catabolic process; Notch signaling pathway; oxalic acid secretion; proteasomal protein catabolic process; pyruvate biosynthetic process; response to cAMP; response to glucocorticoid stimulus |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O35423 |
NCBI GenInfo Identifier: | 111038130 |
NCBI Gene ID: | 11611 |
NCBI Accession: | NP_057911.2 |
UniProt Secondary Accession: | O35423,Q8R128 |
UniProt Related Accession: | O35423 |
Molecular Weight: | 45.3 kDa |
NCBI Full Name: | serine--pyruvate aminotransferase, mitochondrial isoform 1 |
NCBI Synonym Full Names: | alanine-glyoxylate aminotransferase |
NCBI Official Symbol: | Agxt |
NCBI Official Synonym Symbols: | AGT; SPT; Agt1; Agxt1 |
NCBI Protein Information: | serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal |
UniProt Protein Name: | Serine--pyruvate aminotransferase, mitochondrial |
UniProt Synonym Protein Names: | Alanine--glyoxylate aminotransferase (EC:2.6.1.44); AGT |
Protein Family: | Serine--pyruvate aminotransferase |
UniProt Gene Name: | Agxt |
UniProt Entry Name: | SPYA_MOUSE |