AGTRAP Antibody, FITC conjugated (PACO36764)
- SKU:
- PACO36764
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | AGTRAP Antibody, FITC conjugated (PACO36764) |
抗体コード: | PACO36764 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Type-1 angiotensin II receptor-associated protein (108-152AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
シノニム: | Type-1 angiotensin II receptor-associated protein (AT1 receptor-associated protein), AGTRAP, ATRAP |
UniProt Protein Function: | AGTRAP: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 1p36.22 Cellular Component: cytoplasm; intracellular membrane-bound organelle; nucleoplasm Molecular Function:protein binding |
NCBI Summary: | This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6RW13 |
NCBI GenInfo Identifier: | 71152303 |
NCBI Gene ID: | 57085 |
NCBI Accession: | Q6RW13.1 |
UniProt Secondary Accession: | Q6RW13,Q5SNV4, Q5SNV5, Q96AC0, Q96PL4, Q9NRW9, A8MVQ5 |
UniProt Related Accession: | Q6RW13 |
Molecular Weight: | 11,948 Da |
NCBI Full Name: | Type-1 angiotensin II receptor-associated protein |
NCBI Synonym Full Names: | angiotensin II receptor associated protein |
NCBI Official Symbol: | AGTRAP |
NCBI Official Synonym Symbols: | ATRAP |
NCBI Protein Information: | type-1 angiotensin II receptor-associated protein |
UniProt Protein Name: | Type-1 angiotensin II receptor-associated protein |
UniProt Synonym Protein Names: | AT1 receptor-associated protein |
Protein Family: | Type-1 angiotensin II receptor-associated protein |
UniProt Gene Name: | AGTRAP |
UniProt Entry Name: | ATRAP_HUMAN |