AGPAT3 Antibody (PACO53170)
- SKU:
- PACO53170
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | AGPAT3 Antibody (PACO53170) |
抗体コード: | PACO53170 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human 1-acyl-sn-glycerol-3-phosphate acyltransferase γ protein (148-304AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: K562 whole cell lysate. All lanes: AGPAT3 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44, 37, 46 kDa. Observed band size: 44 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO53170 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO53170 at dilution of 1:100. |
バックグラウンド: | Converts lysophosphatidic acid, (LPA) into phosphatidic acid, by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acid, C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. Has a preference for arachidonoyl-CoA as a donor. Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity). |
シノニム: | 1-acyl-sn-glycerol-3-phosphate acyltransferase γ (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid, acyltransferase gamma) (LPAAT-gamma), AGPAT3, LPAAT3 |
UniProt Protein Function: | AGPAT3: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.51; Lipid Metabolism - glycerolipid; Acetyltransferase Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; membrane; plasma membrane Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity Biological Process: phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process |
NCBI Summary: | The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NRZ7 |
NCBI GenInfo Identifier: | 12643817 |
NCBI Gene ID: | 56894 |
NCBI Accession: | Q9NRZ7.1 |
UniProt Secondary Accession: | Q9NRZ7,Q3ZCU2, Q6UWP6, Q6ZUC6, Q8N3Q7, Q9NRZ6, D3DSL2 |
UniProt Related Accession: | Q9NRZ7 |
Molecular Weight: | 45,514 Da |
NCBI Full Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
NCBI Synonym Full Names: | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
NCBI Official Symbol: | AGPAT3 |
NCBI Official Synonym Symbols: | LPAAT3; LPAAT-GAMMA1 |
NCBI Protein Information: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
UniProt Protein Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
UniProt Synonym Protein Names: | 1-acylglycerol-3-phosphate O-acyltransferase 3; 1-AGP acyltransferase 3; 1-AGPAT 3; Lysophosphatidic acid acyltransferase gamma; LPAAT-gamma |
Protein Family: | 1-acyl-sn-glycerol-3-phosphate acyltransferase |
UniProt Gene Name: | AGPAT3 |
UniProt Entry Name: | PLCC_HUMAN |