AGA Antibody, Biotin conjugated (PACO24810)
- SKU:
- PACO24810
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | AGA Antibody, Biotin conjugated (PACO24810) |
抗体コード: | PACO24810 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase protein (206-346AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. |
シノニム: | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) (Aspartylglucosaminidase) (Glycosylasparaginase) (N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase) [Cleaved into: Glycosylasparaginase α chain; Glycosylasparaginase β chain], AGA |
UniProt Protein Function: | AGA: a catabolic enzyme, aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. |
UniProt Protein Details: | Protein type:Glycan Metabolism - other glycan degradation; EC 3.5.1.26; Hydrolase Chromosomal Location of Human Ortholog: 4q34.3 Cellular Component: endoplasmic reticulum; lysosome Molecular Function:peptidase activity; N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; protein self-association Biological Process: protein deglycosylation; protein maturation; proteolysis Disease: Aspartylglucosaminuria |
NCBI Summary: | Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jan 2010] |
UniProt Code: | P20933 |
NCBI GenInfo Identifier: | 288558804 |
NCBI Gene ID: | 175 |
NCBI Accession: | P20933.2 |
UniProt Secondary Accession: | P20933,Q4W5Q2, Q6FHN6, Q9UCK6, Q9UCK7, Q9UCK8, B2R7H2 D3DP47, |
UniProt Related Accession: | P20933 |
Molecular Weight: | 346 |
NCBI Full Name: | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase |
NCBI Synonym Full Names: | aspartylglucosaminidase |
NCBI Official Symbol: | AGA |
NCBI Official Synonym Symbols: | GA; AGU; ASRG |
NCBI Protein Information: | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; glycosylasparaginase; aspartylglucosylamine deaspartylase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase |
UniProt Protein Name: | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase |
UniProt Synonym Protein Names: | Aspartylglucosaminidase; Glycosylasparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidaseCleaved into the following 2 chains:Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain |
Protein Family: | Agaricus bisporus lectin |
UniProt Gene Name: | AGA |
UniProt Entry Name: | ASPG_HUMAN |