ADRB3 Antibody (PACO17500)
- SKU:
- PACO17500
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | ADRB3 Antibody (PACO17500) |
抗体コード: | PACO17500 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
反応性: | Human |
免疫原: | Synthetic peptide of human ADRB3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO17500(ADRB3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene belongs to the family of β adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. |
シノニム: | Adrenoceptor β 3 |
UniProt Protein Function: | ADRB3: Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 8p12 Cellular Component: integral to plasma membrane; plasma membrane; receptor complex Molecular Function:beta-adrenergic receptor activity; beta3-adrenergic receptor activity; epinephrine binding; norepinephrine binding; protein binding; protein homodimerization activity Biological Process: adenylate cyclase activation; arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway; carbohydrate metabolic process; cell-cell signaling; energy reserve metabolic process; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to cyclic nucleotide second messenger; generation of precursor metabolites and energy; norepinephrine-epinephrine vasodilation involved in regulation of systemic arterial blood pressure; positive regulation of MAPKKK cascade; receptor-mediated endocytosis; thermoregulation Disease: Obesity |
NCBI Summary: | The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009] |
UniProt Code: | P13945 |
NCBI GenInfo Identifier: | 461604 |
NCBI Gene ID: | 155 |
NCBI Accession: | P13945.3 |
UniProt Secondary Accession: | P13945,Q4JFT4, |
UniProt Related Accession: | P13945 |
Molecular Weight: | 43,519 Da |
NCBI Full Name: | Beta-3 adrenergic receptor |
NCBI Synonym Full Names: | adrenoceptor beta 3 |
NCBI Official Symbol: | ADRB3 |
NCBI Official Synonym Symbols: | BETA3AR |
NCBI Protein Information: | beta-3 adrenergic receptor |
UniProt Protein Name: | Beta-3 adrenergic receptor |
UniProt Synonym Protein Names: | Beta-3 adrenoreceptor; Beta-3 adrenoceptor |
Protein Family: | Beta-3 adrenergic receptor |
UniProt Gene Name: | ADRB3 |
UniProt Entry Name: | ADRB3_HUMAN |