ADRA2B Antibody (PACO03538)
- SKU:
- PACO03538
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ADRA2B Antibody |
抗体コード: | PACO03538 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | IF:1:200-1:1000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human AR alpha2B. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ADRA2B; ADRA2L1; ADRA2RL1; Alpha-2B adrenergic receptor; Alpha-2 adrenergic receptor subtype C2; Alpha-2B adrenoreceptor; Alpha-2B adrenoceptor; Alpha-2BAR |
UniProt Protein Function: | ADRA2B: Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1 Chromosomal Location of Human Ortholog: 2q11.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:alpha2-adrenergic receptor activity; epinephrine binding; protein binding Biological Process: activation of protein kinase B; cell-cell signaling; G-protein coupled receptor protein signaling pathway; positive regulation of neuron differentiation Disease: Epilepsy, Familial Adult Myoclonic, 2 |
NCBI Summary: | This intronless gene encodes a seven-pass transmembrane protein. This protein is a member of a subfamily of G protein-coupled receptors that regulate neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. [provided by RefSeq, Apr 2014] |
UniProt Code: | P18089 |
NCBI GenInfo Identifier: | 613504690 |
NCBI Gene ID: | 151 |
NCBI Accession: | P18089.3 |
UniProt Secondary Accession: | P18089,Q4TUH9, Q53RF2, Q9BZK0, |
UniProt Related Accession: | P18089 |
Molecular Weight: | 49,566 Da |
NCBI Full Name: | Alpha-2B adrenergic receptor |
NCBI Synonym Full Names: | adrenoceptor alpha 2B |
NCBI Official Symbol: | ADRA2B |
NCBI Official Synonym Symbols: | FAME2; ADRA2L1; ADRARL1; ADRA2RL1; ALPHA2BAR; alpha-2BAR |
NCBI Protein Information: | alpha-2B adrenergic receptor |
UniProt Protein Name: | Alpha-2B adrenergic receptor |
UniProt Synonym Protein Names: | Alpha-2 adrenergic receptor subtype C2; Alpha-2B adrenoreceptor; Alpha-2B adrenoceptor; Alpha-2BAR |
Protein Family: | Alpha-2B adrenergic receptor |
UniProt Gene Name: | ADRA2B |
UniProt Entry Name: | ADA2B_HUMAN |