ADH1B Antibody (PACO24771)
- SKU:
- PACO24771
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ADH1B Antibody (PACO24771) |
抗体コード: | PACO24771 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Alcohol dehydrogenase 1B protein (2-375AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: ADH1B antibody at 2µg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 40, 36 kDa Observed band size: 40 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO24771 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO24771 at dilution of 1:100. |
バックグラウンド: | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and γ subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, β and γ subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene |
シノニム: | Alcohol dehydrogenase 1B (EC 1.1.1.1) (Alcohol dehydrogenase subunit beta), ADH1B, ADH2 |
UniProt Protein Function: | ADH1B: Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.1; Oxidoreductase; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 4q23 Cellular Component: cytosol Molecular Function:zinc ion binding; alcohol dehydrogenase activity, zinc-dependent Biological Process: xenobiotic metabolic process; ethanol oxidation Disease: Alcohol Dependence |
NCBI Summary: | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
UniProt Code: | P00325 |
NCBI GenInfo Identifier: | 113394 |
NCBI Gene ID: | 125 |
NCBI Accession: | P00325.2 |
UniProt Secondary Accession: | P00325,Q13711, Q4ZGI9, Q96KI7, A8MYN5, B4DRS9, B4DVC3 |
UniProt Related Accession: | P00325 |
Molecular Weight: | 375 |
NCBI Full Name: | Alcohol dehydrogenase 1B |
NCBI Synonym Full Names: | alcohol dehydrogenase 1B (class I), beta polypeptide |
NCBI Official Symbol: | ADH1B |
NCBI Official Synonym Symbols: | ADH2; HEL-S-117 |
NCBI Protein Information: | alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; epididymis secretory protein Li 117; alcohol dehydrogenase 2 (class I), beta polypeptide |
UniProt Protein Name: | Alcohol dehydrogenase 1B |
UniProt Synonym Protein Names: | Alcohol dehydrogenase subunit beta |
Protein Family: | Alcohol dehydrogenase |
UniProt Gene Name: | ADH1B |
UniProt Entry Name: | ADH1B_HUMAN |
Antibodies |
Anti-ADH1B Antibody (CAB1431) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |