ADGRB2 Antibody (PACO55086)
- SKU:
- PACO55086
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ADGRB2 Antibody (PACO55086) |
抗体コード: | PACO55086 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Adhesion G protein-coupled receptor B2 protein (1371-1545AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat brain tissue. All lanes: ADGRB2 antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 173, 172, 170 kDa. Observed band size: 173 kDa. | |
Immunofluorescent analysis of HepG2 cells using PACO55086 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway. Might be involved in angiogenesis inhibition (By similarity). |
シノニム: | Adhesion G protein-coupled receptor B2 (Brain-specific angiogenesis inhibitor 2), ADGRB2, BAI2 |
UniProt Protein Function: | BAI2: Might be involved in angiogenesis inhibition. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 1p35.2 |
NCBI Summary: | This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
UniProt Code: | O60241 |
NCBI GenInfo Identifier: | 229462818 |
NCBI Gene ID: | 576 |
NCBI Accession: | O60241.2 |
UniProt Secondary Accession: | O60241,Q5T6K0, Q8NGW8, Q96GZ9, B9EGK9, |
UniProt Related Accession: | O60241 |
Molecular Weight: | 173kDa |
NCBI Full Name: | Adhesion G protein-coupled receptor B2 |
NCBI Synonym Full Names: | adhesion G protein-coupled receptor B2 |
NCBI Official Symbol: | ADGRB2 |
NCBI Official Synonym Symbols: | BAI2 |
NCBI Protein Information: | adhesion G protein-coupled receptor B2 |
UniProt Protein Name: | Adhesion G protein-coupled receptor B2 |
UniProt Synonym Protein Names: | Brain-specific angiogenesis inhibitor 2 |
UniProt Gene Name: | ADGRB2 |