ADGRA2 Antibody, FITC conjugated (PACO54556)
- SKU:
- PACO54556
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ADGRA2 Antibody, FITC conjugated (PACO54556) |
抗体コード: | PACO54556 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Adhesion G protein-coupled receptor A2 protein (1069-1338AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Endothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate. |
シノニム: | Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5), ADGRA2, GPR124 KIAA1531 TEM5 |
UniProt Protein Function: | GPR124: Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GPCR, family 2; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 8p11.23Cellular Component: cell surface; integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; regulation of chemotaxis; central nervous system development; endothelial cell migration; sprouting angiogenesis; regulation of angiogenesis |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q96PE1 |
NCBI GenInfo Identifier: | 221222450 |
NCBI Gene ID: | 25960 |
NCBI Accession: | Q96PE1.2 |
UniProt Secondary Accession: | Q96PE1,Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4, A6H8W3 D3DSW4 |
UniProt Related Accession: | Q96PE1 |
Molecular Weight: | 19,530 Da |
NCBI Full Name: | G-protein coupled receptor 124 |
NCBI Synonym Full Names: | G protein-coupled receptor 124 |
NCBI Official Symbol: | GPR124 |
NCBI Official Synonym Symbols: | TEM5 |
NCBI Protein Information: | G-protein coupled receptor 124; tumor endothelial marker 5 |
UniProt Protein Name: | G-protein coupled receptor 124 |
UniProt Synonym Protein Names: | Tumor endothelial marker 5 |
Protein Family: | |
UniProt Gene Name: | GPR124 |
UniProt Entry Name: | GP124_HUMAN |