ACTR3B Antibody (PACO43432)
- SKU:
- PACO43432
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ACTR3B Antibody (PACO43432) |
抗体コード: | PACO43432 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Actin-related protein 3B protein (189-418AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO43432 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO43432 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO43432 at dilution of 1:100. |
バックグラウンド: | Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. |
シノニム: | Actin-related protein 3B (ARP3-beta) (Actin-like protein 3B) (Actin-related protein ARP4), ACTR3B, ARP11 ARP4 |
UniProt Protein Function: | ACTR3B: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors. Belongs to the actin family. ARP3 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 7q36.1 Cellular Component: Arp2/3 protein complex; cell projection; cytoplasm Molecular Function:actin binding; ATP binding |
NCBI Summary: | This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q9P1U1 |
NCBI GenInfo Identifier: | 74753111 |
NCBI Gene ID: | 57180 |
NCBI Accession: | Q9P1U1.1 |
UniProt Secondary Accession: | Q9P1U1,Q7Z526, Q96BT2, A8MTG1, B4DFW4, |
UniProt Related Accession: | Q9P1U1 |
Molecular Weight: | 418 |
NCBI Full Name: | Actin-related protein 3B |
NCBI Synonym Full Names: | ARP3 actin-related protein 3 homolog B (yeast) |
NCBI Official Symbol: | ACTR3B |
NCBI Official Synonym Symbols: | ARP11; ARP3BETA |
NCBI Protein Information: | actin-related protein 3B; ARP3-beta; actin-like protein 3B; actin-related protein ARP4; actin-related protein Arp11; actin-related protein 3-beta |
UniProt Protein Name: | Actin-related protein 3B |
UniProt Synonym Protein Names: | ARP3-beta; Actin-like protein 3B; Actin-related protein ARP4 |
Protein Family: | Actin-related protein |
UniProt Gene Name: | ACTR3B |
UniProt Entry Name: | ARP3B_HUMAN |