ACP1 Antibody (PACO43430)
- SKU:
- PACO43430
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ACP1 Antibody (PACO43430) |
抗体コード: | PACO43430 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Low molecular weight phosphotyrosine protein phosphatase protein (1-158AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity. |
シノニム: | Low molecular weight phosphotyrosine protein phosphatase (LMW-PTP) (LMW-PTPase) (EC 3.1.3.48) (Adipocyte acid, phosphatase) (Low molecular weight cytosolic acid, phosphatase) (EC 3.1.3.2) (Red cell acid, phosphatase 1), ACP1 |
UniProt Protein Function: | ACP1: a phosphotyrosine protein phosphatase. Functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. Hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. Genetically polymorphic with three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Three transcript variants encoding distinct isoforms have been identified for this gene. |
UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.48; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 2p25 Cellular Component: internal side of plasma membrane; cytoplasm Molecular Function:protein binding; acid phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity |
NCBI Summary: | The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008] |
UniProt Code: | P24666 |
NCBI GenInfo Identifier: | 1709543 |
NCBI Gene ID: | 52 |
NCBI Accession: | P24666.3 |
UniProt Related Accession: | P24666 |
Molecular Weight: | Molecular Mass: 19.04kDaActual Protein Molecular Mass: 18kDa |
NCBI Full Name: | Low molecular weight phosphotyrosine protein phosphatase |
NCBI Synonym Full Names: | acid phosphatase 1 |
NCBI Official Symbol: | ACP1 |
NCBI Official Synonym Symbols: | HAAP; LMWPTP; LMW-PTP |
NCBI Protein Information: | low molecular weight phosphotyrosine protein phosphatase |
UniProt Protein Name: | Low molecular weight phosphotyrosine protein phosphatase |
UniProt Synonym Protein Names: | Adipocyte acid phosphatase; Low molecular weight cytosolic acid phosphatase (EC:3.1.3.2); Red cell acid phosphatase 1 |
Protein Family: | Low molecular weight phosphotyrosine protein phosphatase |
UniProt Gene Name: | ACP1 |
UniProt Entry Name: | PPAC_HUMAN |