ACOX3 Antibody (PACO15266)
- SKU:
- PACO15266
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ACOX3 Antibody (PACO15266) |
抗体コード: | PACO15266 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Fusion protein of human ACOX3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15266(ACOX3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15266(ACOX3 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acid, in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid, protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. |
シノニム: | acyl-CoA oxidase 3, pristanoyl |
UniProt Protein Function: | ACOX3: Oxidizes the CoA-esters of 2-methyl-branched fatty acids. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 1.3.3.6; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - fatty acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 4p16.1 Cellular Component: membrane; peroxisomal matrix; peroxisome Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding Biological Process: fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis |
NCBI Summary: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15254 |
NCBI GenInfo Identifier: | 156104864 |
NCBI Gene ID: | 8310 |
NCBI Accession: | NP_003492.2 |
UniProt Secondary Accession: | O15254,Q96AJ8, |
UniProt Related Accession: | O15254 |
Molecular Weight: | 69,575 Da |
NCBI Full Name: | peroxisomal acyl-coenzyme A oxidase 3 isoform a |
NCBI Synonym Full Names: | acyl-CoA oxidase 3, pristanoyl |
NCBI Official Symbol: | ACOX3 |
NCBI Protein Information: | peroxisomal acyl-coenzyme A oxidase 3 |
UniProt Protein Name: | Peroxisomal acyl-coenzyme A oxidase 3 |
UniProt Synonym Protein Names: | Branched-chain acyl-CoA oxidase; BRCACox; Pristanoyl-CoA oxidase |
Protein Family: | Peroxisomal acyl-coenzyme A oxidase |
UniProt Gene Name: | ACOX3 |
Antibodies |
Anti-ACOX3 Antibody (CAB17020) |
Secondary Antibody |
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