ABI2 Antibody, Biotin conjugated (PACO52989)
- SKU:
- PACO52989
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | ABI2 Antibody, Biotin conjugated (PACO52989) |
抗体コード: | PACO52989 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Abl interactor 2 protein (164-452AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. |
シノニム: | Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1), ABI2, ARGBPIA |
UniProt Protein Function: | Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Adaptor/scaffold; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q33 Cellular Component: cytoskeleton; lamellipodium; cytoplasm; cytosol; filopodium Molecular Function:protein binding; DNA binding; ubiquitin protein ligase binding; Rac GTPase binding; protein complex binding; cytoskeletal adaptor activity; kinase binding; SH3 domain binding Biological Process: cell migration; peptidyl-tyrosine phosphorylation; actin polymerization and/or depolymerization; Rac protein signal transduction; cytoskeleton organization and biogenesis; cell motility |
UniProt Code: | Q9NYB9 |
NCBI GenInfo Identifier: | 50400673 |
NCBI Gene ID: | 10152 |
NCBI Accession: | Q9NYB9.1 |
UniProt Related Accession: | Q9NYB9 |
Molecular Weight: | 56 kDa |
NCBI Full Name: | Abl interactor 2 |
NCBI Synonym Full Names: | abl interactor 2 |
NCBI Official Symbol: | ABI2 |
NCBI Official Synonym Symbols: | AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB |
NCBI Protein Information: | abl interactor 2 |
UniProt Protein Name: | Abl interactor 2 |
UniProt Synonym Protein Names: | Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1 |
Protein Family: | Abl interactor |
UniProt Gene Name: | ABI2 |
UniProt Entry Name: | ABI2_HUMAN |