UniProt Protein Function: | ABCC10: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: lysosomal membrane; integral to membrane; plasma membrane Molecular Function:ATPase activity, coupled to transmembrane movement of substances; ATP binding Biological Process: metabolic process; transmembrane transport |
NCBI Summary: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010] |
UniProt Code: | Q5T3U5 |
NCBI GenInfo Identifier: | 312176403 |
NCBI Gene ID: | 89845 |
NCBI Accession: | NP_001185863.1 |
UniProt Secondary Accession: | Q5T3U5,Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48, |
UniProt Related Accession: | Q5T3U5 |
Molecular Weight: | 161,629 Da |
NCBI Full Name: | multidrug resistance-associated protein 7 isoform MRP7 |
NCBI Synonym Full Names: | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
NCBI Official Symbol: | ABCC10 |
NCBI Official Synonym Symbols: | MRP7; SIMRP7; EST182763 |
NCBI Protein Information: | multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10 |
UniProt Protein Name: | Multidrug resistance-associated protein 7 |
UniProt Synonym Protein Names: | ATP-binding cassette sub-family C member 10 |
UniProt Gene Name: | ABCC10 |
UniProt Entry Name: | MRP7_HUMAN |